Team: Laveena Munshi (co-PI), Sangeeta Mehta (co-PI), Farah Shoukat (COHO-RC), Sumesh Shah (Mount Sinai-RC) + Canadian COHO Collaborators
Background
Recently, there have been important advances in survival outcomes for patients with hematologic malignancies related to enhanced diagnostics and treatment regimens including blood/marrow transplantation. In light of these successful outcomes, aggressive treatment has been extended to higher risk candidates including those who are older, have more comorbid illness and who may receive salvage chemotherapy, dose-intensive regimens, or novel approaches to hematopoietic cell transplantation. As a direct consequence, there has been an increased risk of serious complications and need for ICU care.
Objective
To evaluate determinants of ICU and 1‐year survival and physical disability in critically ill adults with hematologic malignancy admitted to an intensive care unit in Canada.